---
title: "Resolving HTTPS Connection Issues with OmicsBox"
canonical: "https://help.biobam.com/space/OBFAQ/4093837314/Resolving+HTTPS+Connection+Issues+with+OmicsBox"
format: markdown
---
**Issue: OmicsBox fails to connect or transfer data due to SSL inspection by a firewall.**

**Cause:**  
This problem occurs when a network firewall inspects SSL/TLS packages. OmicsBox doesn't recognize the CA Root Certificate of the certificate that signs the SSL responses from the firewall, causing connection or data transfer failures.

**Solution:**  
Follow these steps to resolve the issue:

1. **Import the CA Root Certificate into OmicsBox:**
  - Navigate to `File` -> `Preferences` -> `Proxy` tab.
  - Alternatively, you can access the Proxy Settings from the Activation window.
  - [Learn how to import CA Root Certificates](https://docs.omicsbox.biobam.com/latest/Preferences/#custom-ca-root-certificates)
2. **Obtain the CA Root Certificate:**
  - Request the `ca_root.crt` file from your IT department.
  - Alternatively, you can export the certificate from your browser by following this guide: [Exporting CA Certificates](https://docs.bvstools.com/home/ssl-documentation/exporting-certificate-authorities-cas-from-a-website)
3. **If you continue to experience data transfer issues after activating OmicsBox:**
  - Ask your IT department to exclude the following domains from SSL inspection:
    - `*.s3-accelerate.amazonaws.com`
    - `*.biobam.com`
  This will help prevent SSL inspection from interfering with data transfers between OmicsBox and the cloud.

**Why is this necessary?**  
OmicsBox relies on cloud services for data processing, including uploading data, downloading results, and scheduling tasks. If the firewall inspects SSL traffic, it can block these processes, causing delays or errors.

**For further assistance:**  
If the issue persists after following these steps, please contact our support team.